PTSE® 12/36 – pharma extruder for APIs and more

Intended use

The Pharma Twin Screw Extruder PTSE® 12/36 is used for early development and preparation of samples for clinical studies. As only small batch sizes are needed for the tests, the pharma extruder is well suited for expensive active pharmaceutical substances (APIs). 

Pharma Twin Screw Extruder PTSE 12/36

  • Small batch size
  • Easy cleaning and handling
  • Removable liners
  • Fast and accurate temperature regulation
  • Multiple feeding openings (top and side)
  • Modular system


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Fast and continuous extrusion process for the pharmaceutical industry

Using the GMP qualifiable scale-up extruder you will profit from small batch sizes. You will waste less material and thus save money, particularly when running a test with ex-pensive materials such as APIs.
Moreover, you can reach and clean all components which have contact with the used material easily having a clam shell barrel, removable liners, segmented screws and surfaces made of smooth steel. All material certificates of these components are rec-orded in a list. 

  • Additives
  • Starch
  • Inorganic minerals
  • Pharmaceutical mixtures
  • Plasticizer
  • Solubility enhancement of poorly soluble APIs
  • Taste masking of poorly tasting APIs
  • Rapid method for production of films
  • Modify drug release properties – reduced risk of dose dumping
  • Wet extrusion
  • Wet granulation 
  • Conveyor belt (GMP qualifiable)
  • Granulator (GMP qualifiable)
  • Gravimetric und volumetric feeding systems (GMP qualifiable)
  • Liquid feeding systems (GMP qualifiable)
  • Containment systems (GEA) e.g. Buck® System, Hicoflex® – Charge Bag

Easy process control and data recording with the WinExt® Software including

  • Feeding rate
  • Temperature of the feeding zone
  • Temperature of the heating zones and of the die head
  • Screw speed
  • Product temperature
  • Pressure
  • Torque
  • Speed of the conveyor belt
  • Granulator speed
diameter12 mm
Process length36 D
Max. temperatur200º C (optional 300 °C)
Max. pressure150 bar
Max. torque15 Nm/screw
speed1- 600 rpm
dimensions (L x W x H)1340 mm x 700 mm x 1170 mm
Temperature Control
• Heating
• Cooling
6 Controlled extruder zones
• Electrical
• Integrated controlled water cooling
Downstream Feeding
• Upper
• Side
Liquid, powder or micro pellets (max. 1,5 mm)
• 0D, 10D and 27D
• 12D
Segmented Screw ElementsConveying & kneading elements
Throughput 0,08 to 1 kg/h
System ControlCAN- open bus technology
Drive Motor 3.2 kW Inverter drive
Mains Power3 x 400 V + N + PE, 50/60 Hz, 32A
Weight350 kg

Brochure Pharmaceutical Extrusion Solutions